Publications
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Just out: The reproducible LC-MS human plasma metabolome
Human plasma is a well-studied biofluid in terms of its metabolite composition, as shown by the thousands of entries in the Human Metabolome Database. However, not even nearly all of them are every time detectable by untargeted LC-MS when analysing typical fasting plasma samples. Therefore, we collaborated with Chalmers University of Technology and the International
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Impact of processing on the composition of plant-based foods
Impact of processing on the biochemical composition of plant-based foods published in Nature Food! Our research studying the impact of various processing techniques on the biochemical composition of plant-based foods was recently published in Nature Food. We conducted a non-targeted metabolomics analysis on a variety of plant-based protein-rich foods (PBPR) made using different raw materials and
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Early lifestyle changes may reduce risks for chronic diseases
Our recent publication from the University of Eastern Finland (UEF) has shown that early lifestyle changes, including diet and physical activity interventions during childhood and adolescence, can have long-term effects on metabolism. Metabolomics analysis of The Physical Activity and Nutrition in Children (PANIC) study revealed 80 metabolites linked to key metabolic processes, such as lipid
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Review about indolepropionic acid published
In this review, this time in Finnish :), we summarize the current knowledge about the role of indolepropionic acid (IPA), a gut microbiota metabolite of amino acid tryptophan, in metabolic diseases. In population-based cohorts, higher blood IPA has been associated with reduced risk for type 2 diabetes, low-grade inflammation, cardiovascular diseases, overweight and better liver
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A step towards more consistent metabolite nomenclature
Metabolite identification is a well-known bottleneck in metabolomics analyses, but actually, even when you identify a compound, you will face the situation that the compound is included in various databases and publications with multiple different names – which one to use in your publication? We addressed this issue in our commentary paper just published in