We are excited to announce that original notame has gone through a facelift, and notame, notameViz, and notameStats are now available as Bioconductor packages in the Bioconductor 3.22 release! About the packages A combination of these packages provides an efficient, more reproducible, and more compatible framework for metabolomics data. Altogether, and similarly to the original… Read more: Notame in Bioconductor!

This year marks the final stretch of the HealthFerm project, in which our team has been actively involved in the metabolomics analyses of numerous sample sets developed by our consortium partners. To reflect on progress and strategise, the 3rd Annual HealthFerm Consortium Meeting was held in the student city of Umeå, Sweden, from 8–10 September.… Read more: Throwback: 3rd Annual HealthFerm Meeting in Umeå

Hany will defend his doctoral dissertation at the University of Turku Main building Tauno Nurmela hall on Friday 03 October at 12pm.  The thesis in Food Chemistry is titled “Molecular Insights to Gut–Brain Communication: Metabolomics Approach on Lifestyle Influences”, where the work explores the effect of heavy alcohol and fiber supplementation on gut and brain… Read more: Doctoral defense of Hany Ahmed, MSc, 03 Oct 2025

Human plasma is a well-studied biofluid in terms of its metabolite composition, as shown by the thousands of entries in the Human Metabolome Database. However, not even nearly all of them are every time detectable by untargeted LC-MS when analysing typical fasting plasma samples. Therefore, we collaborated with Chalmers University of Technology and the International… Read more: Just out: The reproducible LC-MS human plasma metabolome

Impact of processing on the biochemical composition of plant-based foods published in Nature Food! Our research studying the impact of various processing techniques on the biochemical composition of plant-based foods was recently published in Nature Food. We conducted a non-targeted metabolomics analysis on a variety of plant-based protein-rich foods (PBPR) made using different raw materials and… Read more: Impact of processing on the composition of plant-based foods

End of January Kati had the possibility to visit London and give a presentation at the Nutrition Society Winter Conference 2025, themed “Dietary guidelines and advice – current and future”. It was great to attend the meeting at the beautiful premises of The Royal Society, and to give an overview of how metabolomics research has… Read more: Throwback: Nutrition Society Winter Conference 2025

Ville Koistinen was awarded a Title of Docent in the discipline of food and nutritional metabolomics by the University of Turku on February 7, 2025. The title in general is awarded based on extensive knowledge in the discipline and good teaching skills, and it translates as Associate professor in those countries where the Title of… Read more: Title of Docent awarded

The HUMAN-DN doctoral network (human-dn.eu) is a multidisciplinary international consortium in which students, professors, and partners worldwide work together to “Harmonise and Unify Blood Metabolomic Analysis Networks”. One of the main project goals is to investigate the implementation of novel blood microsampling in clinical metabolomics and establish suitable workflows for biomarker analysis. Our role here is… Read more: HUMAN-MSCA-DN meeting at the Imperial College of London

The 2024 Nordic Metabolomics Conference was organized  in Tuku, Finland, August 26-28, hosted by Alex Dickens, Kati Hanhineva, and Matej Orešič, with doctoral students Hany Ahmed and Jasmin Raita from our group as part of the organizing committee. This was the first time to have the event in Finland, and it had the highest attendance… Read more: Throwback: 4rd NMC and 33rd BioCity Symposium

Our recent publication from the University of Eastern Finland (UEF) has shown that early lifestyle changes, including diet and physical activity interventions during childhood and adolescence, can have long-term effects on metabolism. Metabolomics analysis of The Physical Activity and Nutrition in Children (PANIC) study revealed 80 metabolites linked to key metabolic processes, such as lipid… Read more: Early lifestyle changes may reduce risks for chronic diseases

In this review, this time in Finnish :), we summarize the current knowledge about the role of indolepropionic acid (IPA), a gut microbiota metabolite of amino acid tryptophan, in metabolic diseases. In population-based cohorts, higher blood IPA has been associated with reduced risk for type 2 diabetes, low-grade inflammation, cardiovascular diseases, overweight and better liver… Read more: Review about indolepropionic acid published

Six of our group members representing the Universities of Eastern Finland and Turku embarked on a journey towards the vibrant city of Osaka, Japan. From June 16th and 20th, we had the opportunity to attend workshops, hear about the latest advancements in the field, and showcase our own research findings.  Our contributions to the scientific… Read more: Throwback to June when Hanhineva Lab enjoyed Metabolomics 2024!

The most conventional and widely used blood sampling method for research purposes is venipuncture (usually from the main veins inside of the elbow). However, this approach may cause distress for the volunteers entering the various types of clinical trials. The sampling also requires professional nurses and often recurring visits to the research facilities for the… Read more: The Future of Blood Testing with Microsampling

Despite the assumption that fermented foods confer numerous health benefits including bioactive compounds synthesis and acute-chronic disease risk reduction, scientific evidence to confirm this conjecture, in terms of grain-based fermentations, is scarce. Further, there is a dearth in valorisation studies to create novel fermented products from the abundant yet underutilized European crops (i.e., wheat, oat,… Read more: Deciphering how grain fermentation shapes the sensomics profile

We are thrilled to share the achievements of Hanhineva Lab at the 3rd Nordic Metabolomics Conference. Our dedicated team had seven representatives actively contributing to the event which took place in Trondheim, Norway October 18-20. Our team showcased our latest research on metabolomics in food and nutrition. We had three oral and five poster presentations,… Read more: Hanhineva Lab at the 3rd Nordic Metabolomics Conference

Ambrin will defend her doctoral thesis in Kuopio on Friday 27 October at 12 pm. The title of her dissertation is A metabolomics approach to delineate the effects of lifestyle intervention and microbiome therapeutics in non-alcoholic fatty liver disease, and the work reveals metabolic alterations in non-alcoholic fatty liver disease (NAFLD) and as a response to… Read more: Doctoral defence of Ambrin Farizah Babu, MSc, 27 Oct 2023

Hanhineva lab will be well represented in Metabolomics 2023 oral and poster sessions. On Monday June 19 at 4:30 pm, two of our team members will give oral presentations. In session Diet and Nutrition, postdoc Topi Meuronen will present some fresh results on the effects of plant-based proteins on serum metabolites (The effect of the… Read more: Hanhineva lab will present recent results in Metabolomics 2023

We are happy to inform you that our research group is participating as a workshop organizer in the 19th Annual Conference of the Metabolomics Society (Niagara Falls, Canada), which is the largest metabolomics meeting worldwide. Our workshop will be held on Monday June 19th at 8.15 – 10.15. We will introduce the preprocessing tool notame… Read more: Welcome to notame workshop in Metabolomics 2023!

Metabolite identification is a well-known bottleneck in metabolomics analyses, but actually, even when you identify a compound, you will face the situation that the compound is included in various databases and publications with multiple different names – which one to use in your publication? We addressed this issue in our commentary paper just published in… Read more: A step towards more consistent metabolite nomenclature

Diets rich in plants are known to have beneficial effects on both the environment and human health. Replacing animal proteins with plant proteins has been suggested to reduce the risk of many major chronic diseases, and whole plant-based ingredients possess high potential for desirable health effects. Yet, the healthiness of plant-based protein-rich products cannot be… Read more: Exploring the impact of protein-rich plant foods on the human gut